目录
硕士报考志愿采集    更新日期:2021年6月29日
姓 名 汪俊松 性 别
出生年月 1975年7月 籍贯 皖无为
民 族 汉族 政治面貌 群众
最后学历 研究生毕业 最后学位 理学博士
技术职称 教授 导师类别 博士生导师
导师类型 校内 兼职导师
行政职务 教研室主任 Email wang.junsong@gmail.com
工作单位 环境与生物工程学院 邮政编码 210094
通讯地址 孝陵卫街200号南京理工大学
单位电话
个人主页 https://ebe.njust.edu.cn/6a/b3/c5080a92851/page.htm
指导学科
学科专业(主) 081703|生物化工 招生类别 博、硕士 所在学院 环境与生物工程学院
研究方向

1.天然药物化学; 2.药理学; 3.系统生物学

学科专业(辅) 0831|生物医学工程 招生类别 硕士 所在学院 环境与生物工程学院
研究方向

1.天然药物化学; 2.药理学; 3.系统生物学

学科专业(辅) 0830|环境科学与工程 招生类别 博、硕士 所在学院 环境与生物工程学院
研究方向

环境毒理

工作经历
1996年7月-1999年8月,安徽省中药材公司质检员;
2007年2月-2008年2月,在世界著名的亚历山大•冯•洪堡基金会资助下作为洪堡学者在德国癌症研究中心开展研究工作;
2008年3月-2013年1月,作为海外引进人才供职中国药科大学中药学院(直聘副教授);
2013年2月至今,南京理工大学环境与生物工程学院、分子代谢中心教授。
教育经历
1992年9月-1996年7月,安徽中医药大学药学院中药系获得中药学学士学位;
1999年9月-2005年3月,于中科院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室进行研究并获得理学博士学位;
2005年9月-2007年1月,于韩国生命工学研究院进行博士后研究。
社会、学会及学术兼职

世界中医药学会联合会中药化学专业委员会理事,世界中医药联合会中药上市后再评价专业委员会理事,中国腐植酸工业协会医药专业委员会委员。Journal of Health Science, Austin Journal of Nutrition & Metabolism, Global Clinical and Translational Research, Global Clinical and Translational Research, Herbal Medicines Journal, 世界科学技术-中医药现代化杂志编委。

科研项目

近5年年均新增到账科研经费50万元。参与并获得省部级、国家级科技奖励成果共四项,发表SCI论文175篇,其中第一作者或通讯作者的SCI论文90篇, H指数37。

文章列表:

http://scholar.google.com/citations?user=DalIGdAAAAAJ

http://orcid.org/0000-0002-8935-4969

发表论文

1. Xu, D.Q; Liao, S.T.; Lv, Y.; Wang, J.S.*; Kong, L.Y.*, NMR-based metabolomics approach revels effects of antioxidant nutrients in sepsis-induced changes in rats liver injury. The Journal of Nutritional Biochemistry 2020, 108440. Doi:10.1016/j.jnutbio.2020.108440 (Impact Factor: 4.873)

2. Luo, H.Z.; Guan, Y.; Yang, R.; Qian, G.L.; Yang, X.H.; Wang, J.S.*; Jia, A.Q.*, Growth inhibition and metabolomic analysis of Xanthomonas oryzae pv. oryzae treated with resveratrol. BMC microbiology 2020, 20, 1-13 (Impact Factor: 2.989).

3. Cui, S.N.*; Li, M.H; Hassan, R.Y.; Heintz-Buschart, A.; Wang, J.S.*; Bilitewski, U.*, Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages. Msphere 2020, 5 (2), e00016-20 (Impact Factor: 4.282).

4. Xu, H.; Ruan, L.Y.; Chen, C.; Fan, J.T.; Chen, J.F.; Zhao, W.L.; Meng, H.H.; Liu, W.Y.; Zhao, W.L.; Zheng, Q. ; Liu. Z.C.; Wang, J.S.*,Therapeutic assessment of fractions of Gastrodiae Rhizoma on chronic atrophic gastritis by 1H NMR-based metabolomics. Journal of Ethnopharmacology 2020 (254), 112403 (Impact Factor: 3.69).

5. Liao, S.T.#; Han, C.#; Xu, D.Q.; Fu, X.W.; Wang, J.S.*; Kong, L.Y.*, 4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects. Nature Communications, 2019, 10 (1), 1-11. (Impact Factor: 11.878)

6. Feng, X.#; Xu, H.#; Chen, J.F.; Ruan, L.Y.; Zhao, W.L.; Meng, H.H.; Liu, W.Y.; Zhao, W.L.; Zheng, Q.; Liu, Z.C.; Kan, Z.B.; Zhong, G.J.; Wang, J.S.*, Potential hepatoxicity risk of the shell of Herpetospermum caudigerum Wall in rats based on 1H-NMR metabonomics. Journal of Pharmaceutical and Biomedical Analysis 2019, 176, 112800. (Impact Factor: 2.983)

7. Yu, X.W.; Wei, D.D.; Gao, Y.S.; Du, H.Z.; Yu, B.Y.; Li, R.M.; Qian, C.M.; Luo, X.J.; Yuan, S.T. *; Wang, J.S.*, Sun, L.*, Synergistic combination of DT-13 and Topotecan inhibits aerobic glycolysis in human gastric carcinoma BGC‐823 cells via NM IIA/EGFR/HK II axis. Journal of Cellular and Molecular Medicine 2019, DOI: 10.1111/jcmm.14523. (Impact Factor: 4.41)

8. Wu, Z.Q.; Zhao, D.D.; Li, S.W.; Wang, J.S.*; Bi, C.H.*; Zhang, X.L.*, Combinatorial modulation of initial codons for improved zeaxanthin synthetic pathway efficiency in Escherichia coli. MicrobiologyOpen 2019, DOI: 10.1002/mbo3.930. (Impact Factor: 2.80)

9. Zhou, J.W.; Muhammad, J.; Sun, B.; Yang, R.; Wadood, A.; Wang, J.S.*; Jia, A.Q.*, Metabolomic analysis of quorum sensing inhibitor hordenine on Pseudomonas aeruginosa. Applied microbiology and biotechnology 2019, 103(15), 6271–6285. (Impact Factor: 3.64)

10. Tang, R.G.; Li, X.G.; Mo, Y.L.; Ma, Y.B.; Ding, C.F.; Wang, J.S.*; Zhang, T.L.; Wang, X.X. *, Toxic responses of metabolites, organelles and gut microorganisms of Eisenia fetida in a soil with chromium contamination. Environmental Pollution 2019, 251, 910-920. (Impact Factor: 5.98)

11. Fu, X.W.; Wang, J.S.*; Liao, S.T.; Lv, Y.; Xu, D.Q.; Yang, M.H.; Kong, L.Y.*, 1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug with Efficacy and a Favorable Therapeutic Window. Frontiers in Pharmacology 2019, 10, 337. (Impact Factor: 3.831)

12. Wu, Z.Q.; Wang, J.S.*; Zhang, X.L*.; Bi, C.H.*, Engineering an electroactive Escherichia coli for the microbial electrosynthesis of succinate by increasing the intracellular FAD pool. Biochemical Engineering Journal 2019, 146, 132-142. (Impact Factor: 3.226)

13. Wu, Z.Q.; Wang, J.S.*; Liu, J.; Wang, Y.; Bi, C.H.*; Zhang, X.L*., Engineering an electroactive Escherichia coli for the microbial electrosynthesis of succinate from glucose and CO2. Microbial Cell Factories 2019, 18 (1), 15. (Impact Factor: 3.831)

14. Zhou, J.W.; Ruan, L.Y.; Chen, H.J.; Luo, H.Z.; Jiang, H.; Wang, J.S.*; Jia, A.Q.*, Inhibition of Quorum Sensing and Virulence in Serratia marcescens by Hordenine. Journal of Agricultural and Food Chemistry 2019, 67 (3), 784-795. (Impact Factor: 3.412)

15. Xu, D.Q.; Liao, S.T.; Li,Pei; Zhang, Q.; Lv, Y.; Fu, X.W.; Yang, M.H.; Wang, J.S.*;  Kong, L.Y.*., Metabolomics Coupled with Transcriptomics Approach Deciphering Age Relevance in Sepsis. Aging and disease, 2019, 10 (4), 854-870 (Impact Factor: 5.058)

16. Chen, C.; Fu, Y.H.; Li, M.H.; Ruan, L.Y.; Xu, H.; Chen, J.F.; Zhao, W.L.; Meng, H.H.; Xing, Y.X.; Hong, W.; Wang, J.S.*, Nuclear magnetic resonance-based metabolomics approach to evaluate preventive and therapeutic effects of Gastrodia elata Blume on chronic atrophic gastritis. Journal of Pharmaceutical and Biomedical Analysis 2019, 164, 231-240. (Impact Factor: 2.831)

17. Ruan, L.Y.; Li, M.H.; Xing, Y.X.; Hong, W.; Chen, C.; Chen, J.F.; Xu, H.; Zhao, W.L.; Wang, J.S.*, Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund. as two sides of the same biological coin. Journal of Ethnopharmacology 2019, 230, 81-94. (Impact Factor: 3.115)

18. Li, M.H.#; Feng, X.#; Deng Ba, D. J.; Chen, C.; Ruan, L.Y.; Xing, Y.X.; Chen, L.Y.; Zhong, G.J.*; Wang, J.S.*, Hepatoprotection of Herpetospermum caudigerum Wall. against CCl4-induced liver fibrosis on rats. Journal of Ethnopharmacology 2019, 229, 1-14. (Impact Factor: 3.115)

19. Li, P.; Liao, S.T.; Wang, J.S.*; Zhang, Q.; Lv, Y.; Yang, M.H.; Kong, L.Y. *, Pharmacokinetic and NMR metabolomics approach to evaluate therapeutic effect of berberine and Coptidis Rhizoma for sepsis. Chinese Herbal Medicines 2019, 11 (1): 28-38

20. Xie, C.L.; Xia, J.M.; Wang, J.S.*; Lin, D.H.*; Yang, X.W.*, Metabolomic Investigations on Nesterenkonia flava Revealed Significant Differences between Marine and Terrestrial Actinomycetes. Marine Drugs 2018, 16 (10), 356. (Impact Factor: 4.379)

21. Feng, X. #; Li, M.H. #; Xia, J.; Deng Ba, D. J.; Ruan, L.Y.; Xing, Y.X.; Chen, C.; Wang, J.S.*; Zhong, G.J.*, Tibetan Medical Formula Shi-Wei-Gan-Ning-Pill Protects Against Carbon Tetrachloride-Induced Liver Fibrosis – An NMR-Based Metabolic Profiling. Frontiers in Pharmacology 2018, 9 (965) (Impact Factor: 3.831)

22. Ruan, L.Y. #; Fan, J.T. #; Hong, W.; Zhao, H.; Li, M.H.; Jiang, L.; Fu, Y.H.; Xing, Y.X.; Chen, C.; Wang, J.S.*, Isoniazid-induced hepatotoxicity and neurotoxicity in rats investigated by 1H NMR based metabolomics approach. Toxicology Letters 2018, 295 (1), 256-269. (Impact Factor: 3.116)

23. Hong, W.; Liu, Y.; Li, M.H.; Xing, Y.X.; Chen, T.; Fu, Y.H.; Jiang, L.; Zhao, H.; Jia, A.Q.*; Wang, J.S.*, In Vivo Toxicology of Carbon Dots by 1H NMR-based metabolomics. Toxicology Research 2018, 7 (5), 834-847. (Impact Factor: 1.890)

24. Xing, Y.X. #; Li, M.H. #; Tao, L.; Ruan, L.Y.; Hong, W.; Chen, C.; Zhao, W.L.; Xu, H.; Chen, J.F.; Wang, J.S.*, Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling. Journal of Proteome Research 2018, 17 (5), 1943-1952. (Impact Factor: 4.268)

25. Lv, Y. #; Tian, N. #; Wang, J.S.*; Yang, M.H.; Kong, L.Y. *, Metabolic switching in the hypoglycemic and antitumor effects of metformin on high glucose induced HepG2 cells. Journal of Pharmaceutical and Biomedical Analysis 2018, 156, 153-162. (Impact Factor :3.255)

26. Li, M.H.; Ruan, L.Y.; Chen, C.; Xing, Y.X.; Hong, W.; Du, R.H.; Wang, J.S.*, Protective effects of Polygonum multiflorum on ischemic stroke rat model analysed by 1H NMR metabolic profiling. Journal of Pharmaceutical and Biomedical Analysis 2018, 155, 91-103. (Impact Factor :3.255)

27. Wan, C.P.#; Li, P.#; Chen, C.Y.; Peng, X.; Li, M.X.; Chen, M.; Wang, J.S.*; Chen, J.Y.*, Antifungal Activity of Ramulus cinnamomi Explored by 1H-NMR Based Metabolomics Approach. Molecules 2017, 22 (12), 2237. (Impact Factor :3.09)

28. Tang, R.G.; Ding, C.F.; Ma, Y.B.; Wang, J.S.*; Zhang, T.L.; Wang, X.X.*, Metabolic Responses of Eisenia Fetida to Individual Pb and Cd Contamination in Two Types of Soils. Scientific Reports 2017, 7 (1), 13110. (Impact Factor :4.259)

29. Lv, Y.; Wang, J.S.*; Xu, D.Q.; Liao, S.T.; Li, P.; Zhang, Q.; Yang, M.H.; Kong, L.Y.*., Comparative study of single/combination use of Huang-Lian-Jie-Du decoction and berberine on their protection on sepsis induced acute liver injury by NMR metabolic profiling. Journal of Pharmaceutical and Biomedical Analysis 2017, 145, 794-804. (Impact Factor :3.255)

30. Li, M.H.; Du, H.Z.; Kong, G.J.; Liu, L.B.; Li, X.X.; Lin, S.S.; Jia, A.Q.; Yuan, S.T.*; Sun, L.*; Wang, J.S.*, Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis. Frontiers in Pharmacology 2017, 8, Article 447, doi: 10.3389/fphar.2017.00447. (Impact Factor: 4.4)

31. Fu, Y.H.; Si, Z.H.; Li, P.M.; Li, M.H.; Zhao, H.; Jiang, L.; Xing, Y.X.; Hong, W.; Ruan, L.Y.; Wang, J.S.*, Acute psychoactive and toxic effects of D. metel on mice explained by 1H NMR based metabolomics approach. Metabolic Brain Disease 2017, 32(4), 1295-1309. (Impact Factor: 2.297)

32. Zhang, Q.; Fu, X.W.; Wang, J.S.*; Yang, M.H.; Kong, L.Y.*, Treatment effects of ischemic stroke by berberine, baicalin and jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) explored by integrated metabolomics approach. Oxidative Medicine and Cellular Longevity 2017, 2017: 9848594. (Impact Factor: 4.593)

33. Zhang, Q.; Wang, J.S.*; Liao, S.; Li, P.; Xu, D.; Lv, Y.; Yang, M.; Kong, L.Y.*, Optimization of Huang-Lian-Jie-Du-Decoction for ischemic stroke treatment and mechanistic study by metabolomic profiling and network analysis. Frontiers in Pharmacology 2017, 8, Article 165, doi: 10.3389/fphar.2017.00165. (Impact Factor: 4.4)

34. Li, M.H.; Ruan, L.Y.; Zhou, J.W.; Fu, Y.H.; Jiang, L.; Zhao, H.; Wang, J.S.*, Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure. Aquatic Toxicology 2017, 188, 159-169. (Impact Factor: 4.129)

35. Xu, D.Q; Lv, Y.; Wang, J.S.*.; Yang, M.H.; Kong, L.Y.*, Deciphering the mechanism of Huang-Lian-Jie-Du-Decoction on the treatment of sepsis by formula decomposition and metabolomics: enhancement of cholinergic pathways and inhibition of HMGB-1/TLR4/NF-κB signaling. Pharmacological Research 2017, 121, 94-113. (Impact Factor: 4.48)

36. Chen, T.T.; Sheng, J.Y.; Fu, Y.H.; Li, M.H.; Wang, J.S.*; Jia, A.Q.*, 1H NMR-Based Global Metabolic Studies of Pseudomonas aeruginosa upon Exposure of the Quorum Sensing Inhibitor Resveratrol. Journal of Proteome Research 2017, 16 (2), 824-830. (Impact Factor: 4.268)

37. Jiang, L.; Si, Z.H.; Li, M.H.; Zhao, H.; Fu, Y.H.; Xing, Y.X.; Hong, W.; Ruan, L.Y.; Li, P.M.; Wang, J.S.*, 1H NMR-based metabolomics study of liver damage induced by ginkgolic acid (15:1) in mice. Journal of Pharmaceutical and Biomedical Analysis 2017, 136, 44-54. (Impact Factor: 3.255)

38. Li, P.#; Liao S.T.#; Wang, J.S.*; Xu, D.Q.; Zhang, Q.#; Xu, D.Q.; Lv, Y.; Yang, M.H.; Kong, L.Y.*, Protection by Huang-Lian-Jie-Du decoction and its constituent herbs of lipopolysaccharide-induced acute kidney injury. FEBS Open Bio 2017, 7(2), 221-236. (Impact Factor: 2.143)

39. Zhao, H.; Si, Z.H.; Li, M.H.; Jiang, L.; Fu, Y.H.; Xing, Y.X.; Hong, W.; Ruan, L.Y.; Li, P.M.; Wang, J.S.*, Pyrazinamide-induced hepatotoxicity and gender differences in rats as revealed by 1H NMR based metabolomics approach. Toxicology Research 2017, 6, 17-29. (Impact Factor : 1.969)

40. Zhang, Q.; Wang, J.S.*; Zhang, C.; Liao S.T.; Li, P.; Xu, D.Q.; Lv, Y.; Yang, M.H.; Kong, L.Y.*, The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model. Oncotarget 2016, 7(49), 80872–80887 (Impact Factor: 5.168)

41. Liao S.T.#; Li, P.#; Wang, J.S.*; Zhang, Q.; Xu, D.Q.; Lv, Y.; Yang, M. H.; Kong, L. Y.*, Huang-Lian-Jie-Du decoction treated sepsis via regulating ERK and SRC/STAT3 pathways and ameliorating metabolic status. RSC Advances 2016, 6 (92), 89855-89866. (Impact Factor: 3.108)

42. Li, P.#; Liao S.T.#; Wang, J.S.*; Xu, D.Q.; Zhang, Q.#; Yang, M.H.; Kong, L.Y.*, NMR metabolic profiling of lipopolysaccharide-induced mice sepsis and the treatment effects of berberine. RSC advances 2016, 6, 47474-47485. (Impact Factor: 3.108)

43. Liao S.T.#; Li, P.#; Wang, J.S.*; Zhang, Q.#; Xu, D.Q.; Yang, M.H.; Kong, L.Y.*, Protection of baicalin on lipopolysaccharide induced liver and kidney injury based on 1H NMR metabolomic profiling. Toxicology Research 2016, 5, 1148-1159. (Impact Factor : 1.969)

44. Li, M.H.; Xu, H.D.; Liu, Y.; Chen, T.; Jiang, L.; Fu, Y. H.; Wang, J.S.*, Multi-tissue metabolic responses of goldfish (Carassius auratis) exposed to glyphosate-based herbicide. Toxicology Research 2016, 5, 1039 - 1052. (Impact Factor : 1.969)

45. Chen, T.; Liu, Y.; Li, M.H.#; Xu, H. D.; Sheng, J.Y.#; Zhang, L.; Wang, J.S.*, Integrated 1H NMR-based metabolomics analysis of earthworm responses to sub-lethal Pb exposure. Environmental Chemistry 2016, 13, 792-803 (Impact Factor : 3.516)

46. Li, P.; Wei, D.D.; Wang, J.S.*; Yang, M.H.; Kong, L.Y.*, 1H NMR metabolomics to study the effects of diazepam on anisatin induced convulsive seizures. Journal of Pharmaceutical and Biomedical Analysis 2016, 117, 184-194. (Impact Factor :3.255)

47. Zhang, Q.; Guo, P.P.; Wang, J.S.*; Yang, M.H.; Kong, L.Y.*, Gender-specific metabolic responses in focal cerebral ischemia of rats and Huang-Lian-Jie-Du decoction treatment. RSC Advances 2015, 5 (116), 95558-95575. (Impact Factor: 3.84)

48. Lou, Y.H; Wang, J.S.*; Dong, G.; Guo, P.P.; Wei, D.D.; Xie, S.S.; Yang, M.H.; Kong, L.Y.*, The acute hepatotoxicity of tacrine explained by 1H NMR based metabolomic profiling. Toxicology Research 2015,4, 1465-1478 (Impact Factor : 3.983)

49. Li, M.H.#; Ruan, L.Y.#; Liu, Y.; Xu, H. D.; Chen, T.; Fu, Y.H.; Jiang, L.; Wang, J.S.*, Insight into biological system responses in goldfish (Carassius auratus) to multiple doses of avermectin exposure by integrated 1H NMR-based metabolomics. Toxicology Research 2015, 4, 1374–1388. (Impact Factor : 2.161)

50. Li, P.C.; Tao, J.; Wei, D.D.; Yang, X.; Lu, Z.G.; Deng, X.H.; Cheng, Y.; Gu, J.B.; Yang, X.J.; Wang, Z.J., Lu, Q.,* Wang, J.S.*, Yin, C.J., Serum metabolomic analysis of human upper urinary tract urothelial carcinoma. Tumor Biology 2015, 36(19): 7531-7537. (Impact Factor : 2.926)

51. Wei, D.D.#; Liao S.T.#; Wang, J.S.*; Yang, M.H.; Kong, L.Y.*, Cholestatic liver injury model of bile duct ligation and the protection of Huang-Lian-Jie-Du decoction by NMR metabolomic profiling. RSC advances 2015, 5, 66200–66211. (Impact Factor: 3.289)

52. Liu, Y.; Chen, T.; Li, M.H.; Xu, H.D.; Jia, A.Q.; Zhang, J.F.; Wang, J.S.*, 1H NMR based metabolomics approach to study the toxic effects of dichlorvos on goldfish (Carassius auratus). Chemosphere 2015, 138, 537-545. (Impact Factor : 3.698)

53. Dong, G.#; Wei, D.D.#; Wang, J.S.*; Guo, P.P; Li, M.H.; Yang, M.H.; Kong, L.Y.*, Study of the cardiotoxicity of Venenum Bufonis in rats using an 1H NMR-based metabolomics approach. Plos one 2015, 10(3): e0119515. (Impact Factor : 3.057)

54. Xiong, Y.Y. #*; Wang, J.S.#; Yu, H.; Zhang, X.L.; Miao, C.G, Anti-asthma potential of crocin and its effect on MAPK signaling pathway in a murine model of allergic airway disease. Immunopharmacology and Immunotoxicology 2015 , 37(3), 236-243. (Impact Factor :1.109)

55. Guo, P.P.#; Wei, D.D. #; Wang, J.S.*; Dong, G.; Zhang, Q; Yang, M.H.; Kong, L.Y.*, Chronic toxicity of crude ricinine in rats assessed by 1H NMR metabolomics analysis. RSC advances 2015, 5, 27018-27028. (Impact Factor: 3.289)

56. Xu, H.D.; Wang, J.S.*; Li, M.H.; Liu, Y.; Chen, T.; Jia, A.Q.*, 1H NMR based metabolomics approach to study the toxic effects of herbicide butachlor on goldfish (Carassius auratus). Aquatic Toxicology 2015, 159, 69-80. (Impact Factor :3.557)

57. Dong G.; Wang, J.S.*; Guo, P.P; Wei D.D.; Yang, M.H.; Kong, L.Y.*, Toxicity assessment of Arisaematis Rhizoma in rats by a 1H NMR-based metabolomics approach. Molecular BioSystems 2015 , 11(2), 407-417. (Impact Factor : 2.829

58. Wei, D.D.; Wang, J.S.*; Li, M.H.; Guo, P.P.; Dong, G.; Yang, M.H.; Kong, L.Y.*, A pilot study of the onset of hepatic encephalopathy (OHE) in mice induced by thioacetamide and the protective effect of taurine by holistic metabolic characterization. Metabolomics 2015, 11 (3), 559-570. (Impact Factor :3.661)

59. Lu, Z.G.; Li, M.H.#; Wang, J.S.*; Wei, D.D.; Liu, Q.W.; Kong, L.Y.*, 1H NMR-based metabolomics study on a goldfish model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chemico-Biological Interactions 2014, 223(5), 18-26. (Impact Factor :2.577

60. Xiong, Y.Y. #*; Wang, J.S. #; Yu, H.; Zhang, X.L.; Miao, C.G.; Ma, S.T., The effects of nodakenin on airway inflammation, hyper-responsiveness and remodeling in a murine model of allergic asthma. Immunopharmacology and Immunotoxicology 2014, 36(5), 341-348. (Impact Factor :1.109)

61. Wei, D.D.#; Dong, G.#; Guo, P.P.; Wang, J.S.*; Li, M.H.; Yang, M.H.; Kong, L.Y.*, A bird's eye view of anisatin induced convulsive seizures in brain by a 1H NMR based metabolic approach. Molecular BioSystems 2014, 10, 2923-2934. (Impact Factor : 3.21)

62. Guo, P.P.; J. Wang, J.S.*; Dong G.; Wei D.D.; Li, M.H.; Yang, M.H.; Kong, L.Y.*, NMR-based metabolomics approach to study the chronic toxicity of crude ricin from castor bean kernels on rats. Molecular BioSystems 2014, 10, 2426-2440. (Impact Factor : 3.21

63. Li, X.; Jia, Y.W.; Wang, J.S.*; Wang, Kelvin; Yang, M.H.; Kong, L.Y.*, 1H nuclear magnetic resonance-based metabolomics reveals sex-specific metabolic changes of gastrodin intervention in rats. Asian Pacific Journal of Tropical Medicine 2014, 7 (10), 811-818. (Impact Factor :0.926

64. Lu, Z.G.#; Li, M.H.#; Wang, J.S.*; Wei, D.D.; Liu, Q.W.; Kong, L.Y.*, Developmental toxicity and neurotoxicity of two matrine-type alkaloids, matrine and sophocarpine, in zebrafish (Danio rerio) embryos/larvae. Reproductive Toxicology 2014, 47 (0), 33-41. (Impact Factor :2.771

65. Wei D.D., Wang J.S.*, Wang P.R., Li, M.H.; Yang, M.H.; Kong, L.Y.*. Toxic effects of chronic low-dose exposure of thioacetamide on rats based on NMR metabolic profiling. Journal of Pharmaceutical and Biomedical Analysis2014, 98, 334-338.  (Impact Factor :2.979)

66. Li, M.H.; Wang, J.S.*; Lu, Z.G.; Wei, D.D.; Yang, M.H.; Kong, L.Y.*, NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus). Aquatic Toxicology 2014, 146, 82-92. (Impact Factor : 3.451)

67. Wang, P.R.; Wang, J.S.*; Yang, M.H.; Kong, L.Y.*, Neuroprotective effects of Huang-Lian-Jie-Du-Decoction on ischemic stroke rats revealed by 1H NMR metabolomics approach. Journal of Pharmaceutical and Biomedical Analysis 2014, 88, 106-116. (Impact Factor : 2.979)

68. Wang, P.R.; Wang, J.S.*; Zhang, C.; Song, X.F.; Tian N.; Kong, L.Y.*, Huang-Lian-Jie-Du-Decotion induced protective autophagy against the injury of cerebral ischemia/reperfusion via MAPK-mTOR signaling pathway. Journal of Ethnopharmacology 2013, 149 (1), 270-280. (Impact Factor :2.939)

69. Yin, P.J.#; Wang, J.S.#; Wei, D.D.; Zhang, Y.; Wang, P.R.; Wang, X.B.; Kong, L.Y.*, Simonols A and B, two novel sesqui-neolignans from the fruits of Illicium simonsii. Fitoterapia 2013, 88, 31-37 (Impact Factor :2.216)

70. Zhang, Y.; Wang, J.S.*; Wei, D.D.; Gu, Y.C.; Wang, X.B.; Kong, L.Y.*, Bioactive Terpenoids from the Fruits of Aphanamixis grandifolia. Journal of Natural Products 2013, 76 (6), 1191-1195. (Impact Factor :3.947)

71. Tian, N.; Wang, J.S.*; Wang, P.R; Song, X.F.; Yang, M.H.; Kong, L.Y.*, NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats. Metabolomics 2013, 9 (6), 1228-1242. (Impact Factor :3.965)

72. Song, X.F.; Wang, J.S.*; Wang, P.R.; Tian N.; Yang, M.H., Kong, L.Y.*, 1H NMR-based metabolomics approach to evaluate the effect of Xue-Fu-Zhu-Yu decoction on hyperlipidemia rats induced by high-fat diet, Journal of Pharmaceutical and Biomedical Analysis 2013, 78-79, 202-210. (Impact Factor :2.829)

 

指导学生情况

合作指导(共同通讯)“全国中医药优秀博士学位论文”一篇(“基于代谢组学的黄连解毒汤治疗脑卒中配伍机制研究”)。