- 主学科0804 仪器科学与技术【博士生导师】
- 二级学科080401|精密仪器及机械
- 研究方向
微流控、芯片实验室、微型反应器
- 跨学科无
- 二级学科无
-
研究方向无
- 专业学位0854 电子信息
-
研究方向无
工作经历
2007年-2014年 新加坡科技研究局制造技术研究院 研究员
2015年-至今 南京理工大学机械工程学院仪器科学与技术系 教授
教育经历
南京航空航天大学 (本科,硕士)
新加坡国立大学 (博士)
2010年 新加坡制造技术研究院 “最佳研究项目”奖
2014年 入选“江苏特聘教授”计划
《Chemical Engineering Journal》、《Industrial & Engineering Chemistry Research》、《Physics of Fluids》、《Microfluidics and Nanofluidics》,《Journal of Micromechanics and Microengineering》等期刊审稿人
科研项目
-
装备发展部,××× 专项子专题,140××××××,××× 制备技术,2018/09~2020/09
-
某产品微反应制备工艺技术研究(I&II), 工业项目,2018/9~2020/12
-
自然科学基金面上项目,51575282,基于水弹性和气动弹性效应的微流体操控机理和方法研究,2016/1~2019/12
-
南京理工大学自主科研专项计划项目,30915118802,基于振荡流的液滴微流控技术研究,2015/11~2018/10
2014年前主要承担和参加的研究项目
-
与南洋理工大学联合研究项目,磁性微流体扩散现象研究(Magnetofluidic spreading),2013/10~2014/12。
-
与新加坡高性能计算研究院联合研究项目,新型微流体混合器和振荡器工作机理及设计优化研究,2013/1~2013/12。
-
工业项目,面向工业实际应用的关键微流控技术研究,2011/11~2013/2。
-
新加坡制造技术研究院研究项目,一种微流体振荡器的设计、表征及应用, 2010/7~2011/6。
-
新加坡制造技术研究院研究项目,多种微型混合器的设计、实现及应用研究,2009/5~2010/4。
-
工业项目,一种便携式床边检测系统的开发,2013/12~2014/12。
-
与新加坡国立大学联合研究项目,基于芯片实验室技术的人类鼻上皮干细胞研究,2012/8~2014/3。
-
与南洋理工大学联合研究项目,表面声波(SAW)微流控技术研究,2012/8~2016/12。
期刊论文
-
C. C. Yuan, Q.Q. Gu, H.C. Fang, H. M. Xia*, An investigation on microfluidic preparation of aluminum phosphate adjuvant, Microfluidics and Nanofluidics, 27:54, 2023.
-
M. Wang, H. M. Xia*, L. Zhu, Y.Y. Zhang, Regulating the gas-liquid slug flow in microchannels through high-frequency pulsatile perturbations, Industrial and Engineering Chemistry Research, 62, 1997-2007, 2023.
-
Y.Y. Zhang, J.M. Wang, J.W. Wu, H. M. Xia*, Numerical study on active droplet generation governed by pulsatile continuous-phase flow, Asia-Pacific Journal of Chemical Engineering, 2023: e2997, 2023.
-
Y.Y. Zhang, H. M. Xia*, PZT actuator-controlled high-frequency microdroplet generation: reducing the restrictions of channel size, fluid viscosity, and flow rate, Sensors and Actuators: B. Chemical, 368,132183, 2022.
-
J. W. Wu, H. M. Xia*, Z. P. Wang, W. Wang, H. J. Du, Analyzing the effects of key design factors of a negative-differential-resistance (NDR) microfluidic oscillator―An equivalent-circuit-model approach, Advances in Applied Mathematics and Mechanics, 14(6), 1381-1399, 2022.
-
J.Y. Shi, P. Zhu, J.Z. Liu, R.Q. Shen, H.M. Xia, H.Y. Jiang, S.Y. Xu, F.Q. Zhao, Coupling oscillating-swirling-coflowing: A microfluidic strategy for superior safety and output performance of core-shell energetic microspheres, Industrial and Engineering Chemistry Research, 61, 17593-17606, 2022.
-
Y.Z. Chu, J.F. Chen, H. M. Xia*, Improving the immunoassay for procalcitonin detection using an aeroelastic agitator: A feasibility study, Sensors & Actuators: A. Physical, 340, 113542, 2022.
-
F. Yan, P. Zhu, S. Zhao, J. Shi, Y. Mu, H.M. Xia, R. Shen, Microfluidic strategy for coating and modification of polymer-bonded nano-HNS explosives, Chemical Engineering Journal, 428, 131096, 2022.
-
H.M. Xia*, J.W. Wu, J.J. Zheng, J. Zhang, Z.P. Wang, Nonlinear microfluidics: Device physics, functions, and applications, Lab on a Chip, 21, 1241-1268, 2021.
-
Y.T. Duan, C.Y. Mao, Y.Y. Zhang, D.Z. Wang, H.M. Xia*, A facile method for Microfluidic metering and transport, Microfluidics and Nanofluidics, 25:94, 2021.
-
J.M. Wang, Q.Q. Jin, Y.Y. Zhang, H.C. Fang, H.M. Xia*, Reducing the membrane fouling in cross-flow filtration using a facile fluidic oscillator, Separation and Purification Technology, 272, 118854, 2021.
-
J.Y. Ning, J. B. Liu, J. Z. Liu, Q.H. Zhang, W.Q. Zhang, H.M Xia, R. Q, Shen, P. Zhu, Multi-parallel microfluidic recrystallization and characterization of explosives, Energetic Materials Frontiers, 2, 278-286, 2021.
-
J. Shi, P. Zhu, S. F. Zhao, C. Xu, F. Yan, R. Q. Shen, H.M. Xia, H. Jiang, S. Xu, F. Zhao, Continuous spheroidization strategy for explosives with micro/nano hierarchical structure by coupling microfluidics and spray drying. Chemical Engineering Journal 412(1), 128613, 2021.
-
L. Zhu, Z.F. Wang, H.M. Xia, H.Yu, Design and fabrication of the vertical-flow bioreactor for compaction hepatocyte culture in drug testing application, Biosensors, 11(5), 160, 2021.
-
X. Zhou, C. Chen, P. Zhu, S.F. Zhao, J.Y. Shi, F. Yan, R.Q. Shen, H.M.Xia, Microreaction system combining chaotic micromixing with fast mixing and particle growth in liquid-segmented flow for the synthesis of hazardous ionic materials, Energetic Materials Frontiers,1(3-4), 186-194, 2020
-
J. Shi, P. Zhu, S. F. Zhao, R. Q. Shen, H.M. Xia, H. Jiang, S. Xu, Microfluidic strategy for rapid and high-quality control of crystal morphology of explosives, Reaction Chemistry & Engineering, 5(6), 1093-1103, 2020. .
-
J. W. Wu, H. M. Xia*, W. Wang, Y. Foo, Z. P. Wang, H. Du, A droplet platform capable of handling dissimilar liquids and its application for separation of bacteria from blood. Biomicrofluidics, 14, 034102, 2020.
-
C. Chen, S. F. Zhao, P. Zhu, J. Y. Shi, F. Yan, H. M. Xia, R.Q. Shen. Improvement of silver azide crystal morphology and detonation behavior by fast mixing using a microreaction system with integrated static micro mixer, Reaction Chemistry & Engineering, 5, 154-162, 2020
-
S.F. Zhao, C. Chen, P. Zhu, H.M. Xia, J. Shi, F. Yan, R. Shen, Passive micromixer platform for size- and shape-controllable preparation of ultrafine HNS, Industrial & Engineering Chemistry Research, 58, 36, 16709-16718, 2019.
-
Y.Y. Zhang, H. M. Xia,* J.W. Wu, J. Zhang, Z.P. Wang, Synchronized generation and coalescence of largely dissimilar microdroplets governed by pulsating continuous-phase flow, Applied Physics Letters, 114, 073701, 2019.
-
J. W. Wu, H. M. Xia,* Y. Y. Zhang, S. F. Zhao, P. Zhu, Z. P. Wang, An efficient micromixer combining oscillatory flow and divergent circular chambers, Microsystem Technologies, 25, 2741-2750, 2019.
-
Y.H. Piao, X.B. Wang, H. M. Xia, W.Q. Wang, Digital microfluidic platform for automated detection of human chorionic gonadotropin, Microfluidics and Nanofluidics, 23:1, 2019.
-
S.F. Zhao, J.W. Wu, P. Zhu, H.M. Xia, C. Chen, R.Q. Shen, A microfluidic platform for preparation and screening of narrow size-distributed nanoscale explosives and supermixed composite explosives, Industrial & Engineering Chemistry Research, 57, 13191-13204, 2018.
-
S.F. Zhao, N. Zhou, P. Zhu, H.M. Xia, Y. Yang, R.Q. Shen, Y.H. Ye, Optimization synthesis of morphologically homogeneous and rod-like barium trinitroresorcinate produced by segmented flow, Journal of Chemical Engineering of Japan, 51(6), 524-529, 2018.
-
J. W. Wu, H. M. Xia*, Y. Y. Zhang, P. Zhu, Microfluidic mixing through oscillatory transverse perturbations, Modern Physics letters B, 32 (12-13), 1840030, 2018.
-
J. Zhang, D. Yuan, Q. Zhao, S. Yan, S.Y. Tang, S. H. Tan, J. Guo, H. M. Xia, et al., Tunable particle separation in a hybrid dielectrophoresis (DEP)-inertial microfluidic device, Sensors and Actuators B: Chemical, 267, 14-25, 2018.
-
S.F. Zhao, F. Yan, P. Zhu, Y. Yang, H. M. Xia, R. Shen, Y.H. Ye, Micro-segmented flow technology applied for synthesis and shape control of lead styphnate micro-Particles, Propellants, Explosives, Pyrotechnics, 43, 286-293, 2018
-
H. M. Xia*, J. W. Wu, Z. P. Wang, A comparative discussion of different designs of passive micromixers: specific sensitivities of mixing efficiency on Reynolds numbers and fluid properties, Microsystem Technologies, 24(2), 1253-1263, 2018.
-
H. M. Xia*, X. Jin, Y.Y. Zhang, J. W. Wu, J. Zhang, Z. P. Wang, Integrated aeroealstic vibrator for fluid mixing in open microwells, Journal of Micromechanics and Microengineering, 28, 017001, 2018.
-
J. Zhang, D. Yuan, R. Sluyter, S. Yan, Q. Zhao. H.M. Xia, et al., High-through separation of white blood cells from whole blood using inertial microfluidics, IEEE Transactions on Biomedical Circuits and Systems, 11(6),1422-1430, 2017.
-
H. M. Xia*, J. W. Wu, Z. P. Wang, The negative-differential-resistance (NDR) mechanism of a hydroelastic microfluidic oscillator, Journal of Micromechanics and Microengineering, 27, 075001, 2017.
-
L. Zhu, H.M. Xia, Z.F. Wang, E. L. S. Fong, J. J. Fan , W. H. Tong, Y. P. D. Seah, W.A. Zhang, Q.S. Li, and H. Yu. Vertical-flow bioreactor array compacts hepatocytes for enhanced polarity and functions, Lab Chip, 16, 3898-3908, 2016.
-
N. Zhou, P. Zhu, Y. Rong, H.M. Xia, R.Q. Shen, Y. H. Ye, S. L. Lv, Microfluidic synthesis of size-controlled and morphologically homogeneous lead trinitroresorcinate produced by segmented flow, Propellants, Explosives, Pyrotechnics, 41, 899-905, 2016.
-
S. Wan, H. M. Xia, K. Pankaj, “Numerical analysis and characterization of a Wankel pump as a miniaturized mixer", Journal of Micromechanics and Microengineering, 25, 084001, 2015.
-
R. Kishor, Y.P Seah, Y.J Zheng, H.M Xia, Z.F. Wang, H.J. Lu, T.T. Lim, “Characterization of an acoustically coupled multilayered microfluidic platform on SAW substrate using mixing phenomena”, Sensors & Actuators A, 233, 360-367, 2015.
-
H. M. Xia*, Y. P. Seah, Y. C. Liu, W. Wang, Alicia G. G. Toh, Z. P. Wang, “Anti-solvent precipitation of solid-lipid nanoparticles using a microfluidic oscillator mixer”, Microfluidics and Nanofluidics, 19, 283-290, 2015.
-
Z. M. Wang, V. B. Varma, H. M. Xia, Z. P. Wang, R. V. Ramanujan, “Spreading of a ferrofluid core in three-stream micromixer channels", Physics of Fluids, 27, 052004, 2015.
-
Z. Z. Chong, W. Jun Sim, Z. T. Yeo, K. H. Li, S. H. Ng, H. M. Xia, T. N. Wong, N. H. Loh, S. B. Tor, S. H. Tan, N.-T. Nguyen, “Elastic magnetic membrane for improved mixing in microwells”, Micro and Nanosystems, 6, 232-236, 2014.
-
H. M. Xia*, Z. P. Wang, V. B. Nguyen, S. H. Ng, W. Wang, F. Y. Leong, D. V. Le, “Analyzing the transition pressure and viscosity limit of a hydroelastic microfluidic oscillator”, Applied Physics Letters, 104, 024101, 2014.
-
W. Wang, Y. Yan, C. W. Li, H. M. Xia, S. S. Chao, D. Y. Wang, Z. P. Wang, “Live Human Nasal Epithelial Cells (hNECs) On Chip for In Vitro Testing of Gaseous Formaldehyde Toxicity via Airway Delivery”, Lab Chip, 14, 677-680, 2014.
-
H. M. Xia*, Z. P. Wang, W. Wang, W. Fan, A. Wijaya, Z. F. Wang, “Aeroelasticity-based fluid agitation for lab-on-chips”, Lab Chip, 13, 1619-1625, 2013.
-
H. M. Xia*, Z. P. Wang, S. Y. M. Wan, F. F. Yin, “Numerical study on microstructured reactor with chaotic heat and mass transfer and its potential application for exothermic process”, Chemical Engineering Research and Design, 90(11), 1719-1726, 2012.
-
H. M. Xia*, Z. P. Wang, F. Wei, A. Wijaya, W. Wang, Z. F. Wang, “Converting steady laminar flow to oscillatory flow through a hydro-elasticity approach at micro scales”, Lab Chip, 12, 60-64, 2012.
-
Z. K. Wang, H. Y. Zheng, H. M. Xia, “Femtosecond laser-induced modification of surface wettability of PMMA for fluid separation in microchannels”, Microfluidics and Nanofluidics, 10, 225-229, 2011.
-
H. M. Xia, Z. P. Wang, Y. X. Koh, K. T. May, “A microfluidic mixer with self-excited ‘turbulent’ fluid motion for wide viscosity ratio applications”, Lab Chip, 10, 1712-1716, 2010.
-
H. M. Xia, C. Shu, Y. T. Chew and Z. P. Wang, “Approximate mapping method for prediction of chaotic mixing in spatial-periodic microchannel”, Chemical Engineering Research and Design, 88 (10), 1419-1426, 2010.
-
L. P. Yeo, S. H. Ng, Z. F. Wang, H. M. Xia, Z. P. Wang, V. S. Thang, Z. W. Zhong, N. F. de Rooij, “Investigation of hot roller embossing for microfluidic devices”, Journal of Micromechanics and Microengineering, 20, 015017, 2010.
-
H. M. Xia, C. Shu, S. Wan, Y. T, Chew, “Influence of Reynolds number on chaotic mixing in spatially periodic micromixer and its characterization using dynamical system techniques”, Journal of Micromechanics and Microengineering, 16, 53-61, 2006.
-
H. M. Xia, S. Wan, C. Shu, Y. T. Chew, “Chaotic micromixers using two-layer crossing channels to exhibit fast mixing at low Reynolds numbers”, Lab Chip, 5, 748-755, 2005.
-
H. M. Xia, C. Shu, S. Wan, Y. T. Chew, “Numerical and experimental observation of chaotic mixing in microfluidic mixer”, Journal of Visualization, 8, 291, 2005.
-
Y. T. Chew, H. M. Xia, C. Shu, S. Wan, “Techniques to enhance fluid micro-mixing and chaotic micromixers”, Modern Physics Letters B, 19, 1567-1570, 2005.
-
S. C. Luo, H. M. Xia, “Parallel vortex shedding at Re = O(10^4) – a transverse control cylinder technique approach”, Journal of Fluid Mechanics, 541, 143-165, 2005.
专利申请
-
夏焕明,王蒙,崔俊雅;一种基于脉冲气流的液滴喷射方法;申请日期 2023.07.07,申请号 2023108301773
-
王蒙,夏焕明;一种基于脉冲气流的泰勒流及液滴制备系统;申请日期 2022.08.31,申请号 202211062799.8
-
夏焕明,茅成跃;一种微流体自动 定量取样方法和系统;申请日期 2021.11.22,申请号 202111388204.3
-
袁超超,夏焕明;一种铝盐疫苗佐剂的微流控制备方法,申请日期 2022.12.08,申请号 202211573839.5
-
初永政,夏焕明,一种流体激励器及流体激励系统,申请日期 2019.05.22,申请号 201910427967.0
-
段钰彤,夏焕明,一种微流控进样系统,发明专利号:ZL 201911108235, 授权日期:2021.05.04
-
夏焕明,张言引,一种基于振荡流的液滴融合方法及器件,发明专利号:ZL 201810266414.7, 授权日期:2021.05.07
-
夏焕明,张言引,一种基于振荡流主动控制的液滴制备方法及器件,发明专利号:ZL 201810267395.X,授权日期:2021.05.13.
-
夏焕明; 赵双飞; 朱朋; 沈瑞琪; 叶迎华, 一种基于微流控技术的纳米炸药制备系统和方法,发明专利号:ZL 201811027496.6, 授权日期:2020.12.25
-
吴嘉炜,夏焕明,一种振荡流微混合器,实用新型专利号:201720098426.4,授权日期 2017.10.10.
-
夏焕明,王志平,吴嘉炜,一种负流阻振荡器,实用新型专利号:201720418413.0,授权日期 2017.10.23.
-
H. M. Xia, Z. P. Wang, W. Wang, Microfluidic Agitator Devices and Methods for Agitation of a Fluid, US Patent No.: US 9364804 B2, Jun 14, 2016.
-
H.M. Xia, Z. P. Wang, Microfluidic Mixing Apparatus and Method, US Patent No.: US 9393535 B2, Jul 19, 2016.
-
H. M. Xia, Z. P. Wang, W. Fan, Z. F. Wang, A microfluidic device for altering a fluid flow and a microfluidic system including the microfluidic device, WO/2012/036627; PCT application No.: PCT/SG2010/000346, 2009.
1. 新生研讨课 《芯片实验室技术漫谈及器件制作》
2.专业课《微系统技术》